Program / Dept 1
Molecular Cell Pharmacology
Program / Dept 2
Short Research Description
Regulation of membrane and organelle dynamics in development and disease
Membership in other UW Grad Training Programs
Integrated Program in Biochemistry, Endocrinology-Reproductive Physiology, Cell and Molecular Biology
The directed movement of proteins and membranes between different cellular locations is a fundamental process required for the proper functioning of all eukaryotic cells. Many diseases including cancer, neurodegenerative disorders such as Parkinson's disease and Huntington's disease, and immune dysfunction can be caused by intracellular protein transport defects. Our goal is to determine how membrane trafficking pathways are appropriately regulated, enhancing our fundamental understanding of this process, which should facilitate the future identification of therapeutic targets for disease intervention.